Targeting mitochondrial apoptosis to overcome treatment resistance in cancer

by Ngoi N.Y.L., Choong C., Lee J., Bellot G., Wong A.L.A., Goh B.C., Pervaiz S.
Published 2020

Targeting metabolism in cancer cells and the tumour microenvironment for cancer therapy

by Li, J., Eu, J.Q., Kong, L.R., Wang, L., Lim, Y.C., Goh, B.C., Wong, A.L.A.
Published 2021

Improving medication adherence with adjuvant aromatase inhibitor in women with breast cancer: Study protocol of a randomised controlled trial to evaluate the effect of short messag...

by He Y., Tan E.H., Wong A.L.A., Tan C.C., Wong P., Lee S.C., Tai B.C.
Published 2019

Gemcitabine and platinum pathway pharmacogenetics in Asian breast cancer patients

by Wong, A.L.-A., Yap, H.-L., Yeo, W.-L., Soong, R., Ng, S.-S., Wang, L.-Z., Cordero, M.T., Yong, W.-P., Goh, B.-C., Lee, S.-C.
Published 2014

Method development and validation for rapid quantification of hydroxychloroquine in human blood using liquid chromatography-tandem mass spectrometry

by Wang, L.-Z., Ong, R.Y.-L., Chin, T.-M., Thuya, W.-L., Wan, S.-C., Wong, A.L.A., Chan, S.-Y., Ho, P.C., Goh, B.-C.
Published 2014

Pan-CDK inhibition augments cisplatin lethality in nasopharyngeal carcinoma cell lines and xenograft models

by Syn N.L., Lim P.L., Kong L.R., Wang L., Wong A.L.-A., Lim C.M., Loh T.K.S., Siemeister G., Goh B.C., Hsieh W.-S.
Published 2019

Improving medication adherence with adjuvant aromatase inhibitor in women with breast cancer: A randomised controlled trial to evaluate the effect of short message service (SMS) re...

by Tan, E.H., Wong, A.L.A., Tan, C.C., Wong, P., Tan, S.H., Ang, L.E.Y., Lim, S.E., Chong, W.Q., Ho, J., Lee, S.C., Tai, B.C.
Published 2021

A review on liquid chromatography-tandem mass spectrometry methods for rapid quantification of oncology drugs

by Wong, A.L.-A, Xiang, X, Ong, P.S, Mitchell, E.Q.Y, Syn, N, Wee, I, Kumar, A.P, Yong, W.P, Sethi, G, Goh, B.C, Ho, P.C.-L, Wang, L
Published 2020

A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics study

by Wang, L, Khoa Phan, D.-D, Syn, N, Xiang, X, Song, H, Thuya, W.L, Yang, S, Wong, A.L.-A, Kumar, A.P, Yong, W.P, Sethi, G, Ho, P.C.-L, Goh, B.C
Published 2020

Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development

by Wang, L, Khoa Phan, D.D, Zhang, J, Ong, P.-S, Thuya, W.L, Soo, R.A, Wong, A.L.-A, Yong, W.P, Lee, S.C, Ho, P.C.-L, Sethi, G, Goh, B.C
Published 2020

Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours

by Soo, R.A, Syn, N, Lee, S.-C, Wang, L, Lim, X.-Y, Loh, M, Tan, S.-H, Zee, Y.-K, Wong, A.L.-A, Chuah, B, Chan, D, Lim, S.-E, Goh, B.-C, Soong, R, Yong, W.-P
Published 2020

Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1

by Wang, L, Chan, C.E.L, Wong, A.L.-A, Wong, F.C, Lim, S.W, Chinnathambi, A, Alharbi, S.A, Lee, L.S.-U, Soo, R, Yong, W.P, Lee, S.C, Ho, P.C.-L, Sethi, G, Goh, B.C
Published 2020

Glucuronidation by UGT1A1 Is the Dominant Pathway of the Metabolic Disposition of Belinostat in Liver Cancer Patients

by Wang, L.-Z., Ramírez, J., Yeo, W., Chan, M.-Y.M., Thuya, W.-L., Lau, J.-Y.A., Wan, S.-C., Wong, A.L.-A., Zee, Y.-K., Lim, R., Lee, S.-C., Ho, P.C., Lee, H.-S., Chan, A., Ansher, S., Ratain, M.J., Goh, B.-C.
Published 2014

Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: A randomized controlled trial

by Syn N.L., Wong A.L.-A., Lee S.-C., Teoh H.-L., Yip J.W.L., Seet R.C.S., Yeo W.T., Kristanto W., Bee P.-C., Poon L.M., Marban P., Wu T.S., Winther M.D., Brunham L.R., Soong R., Tai B.-C., Goh B.-C.
Published 2019

Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib

by Wong A.L.A., Lim J.S.J., Sinha A., Gopinathan A., Lim R., Tan C.-S., Soh T., Venkatesh S., Titin C., Sapari N.S., Lee S.-C., Yong W.-P., Tan D.S.P., Pang B., Wang T.-T., Zee Y.-K., Soong R., Trnkova Z., Lathia C., Thiery J.-P., Wilhelm S., Jeffers M., Goh B.-C.
Published 2018

Phase Ib/II randomized, open-label study of doxorubicin and cyclophosphamide with or without low-dose, short-course sunitinib in the pre-operative treatment of breast cancer

by Wong A.L.A., Sundar R., Wang T.-T., Ng T.-C., Zhang B., Tan S.-H., Soh T.I.P., Pang A.S.L., Tan C.-S., Ow S.G.W., Wang L., Mogro J., Ho J., Jeyasekharan A.D., Huang Y., Thng C.-H., Chan C.-W., Hartman M., Iau P., Buhari S.A., Goh B.-C., Lee S.-C.
Published 2020