Genome-wide approaches to dissect the roles of RNA binding proteins in translational control: Implications for neurological diseases

by Kapeli, K, Yeo, G.W
Published 2020

Genetic mutations in RNA-binding proteins and their roles in ALS

by Kapeli, K, Martinez, F.J, Yeo, G.W
Published 2020

Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells

by van den Hurk, M., Erwin, J.A., Yeo, G.W., Gage, F.H., Bardy, C.
Published 2021

Corrigendum: Patch-seq protocol to analyze the electrophysiology, morphology and transcriptome of whole single neurons derived from human pluripotent stem cells (Front. Mol. Neuros...

by van den Hurk, M., Erwin, J.A., Yeo, G.W., Gage, F.H., Bardy, C.
Published 2021

An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys

by Parra M., Booth B.W., Weiszmann R., Yee B., Yeo G.W., Brown J.B., Celniker S.E., Conboy J.G.
Published 2019

Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9

by Huang, H., Kapeli, K., Jin, W., Wong, Y.P., Arumugam, T.V., Koh, J.H., Srimasorn, S., Mallilankaraman, K., En Chua, J.J., Yeo, G.W., Soong, T.W.
Published 2021

A novel splice-site mutation in ALS establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias

by Siddiqi S., Foo J.N., Vu A., Azim S., Silver D.L., Mansoor A., Tay S.K.H., Abbasi S., Hashmi A.H., Janjua J., Khalid S., Tai E.S., Yeo G.W., Khor C.C.
Published 2018

Sequence, Structure, and Context Preferences of Human RNA Binding Proteins

by Dominguez D., Freese P., Alexis M.S., Su A., Hochman M., Palden T., Bazile C., Lambert N.J., Van Nostrand E.L., Pratt G.A., Yeo G.W., Graveley B.R., Burge C.B.
Published 2019

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP

by Sun S., Ling S.-C., Qiu J., Albuquerque C.P., Zhou Y., Tokunaga S., Li H., Qiu H., Bui A., Yeo G.W., Huang E.J., Eggan K., Zhou H., Fu X.-D., Lagier-Tourenne C., Cleveland D.W.
Published 2016

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

by Yang, E.-W., Bahn, J.H., Hsiao, E.Y.-H., Tan, B.X., Sun, Y., Fu, T., Zhou, B., Van Nostrand, E.L., Pratt, G.A., Freese, P., Wei, X., Quinones-Valdez, G., Urban, A.E., Graveley, B.R., Burge, C.B., Yeo, G.W., Xiao, X.
Published 2021

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

by Kapeli, K, Pratt, G.A, Vu, A.Q, Hutt, K.R, Martinez, F.J, Sundararaman, B, Batra, R, Freese, P, Lambert, N.J, Huelga, S.C, Chun, S.J, Liang, T.Y, Chang, J, Donohue, J.P, Shiue, L, Zhang, J, Zhu, H, Cambi, F, Kasarskis, E, Hoon, S, Ares, M, Burge, C.B, Ravits, J, Rigo, F, Yeo, G.W
Published 2020

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

by Ling, S.-C., Dastidar, S.G., Tokunaga, S., Ho, W.Y., Lim, K., Ilieva, H., Parone, P.A., Tyan, S.-H., Tse, T.M., Chang, J.-C., Platoshyn, O., Bui, N.B., Bui, A., Vetto, A., Sun, S., McAlonis-Downes, M., Han, J.S., Swing, D., Kapeli, K., Yeo, G.W., Tessarollo, L., Marsala, M., Shaw, C.E., Tucker-Kellogg, G., La Spada, A.R., Lagier-Tourenne, C., Da Cruz, S., Cleveland, D.W.
Published 2021