#TITLE_ALTERNATIVE#
Polymethylmethacrylate (PMMA)-based bone cement is one of the most popular materials for implant fixations. These bone cement have limitations, one of them is they do not show bone-bonding characteristic which caused bond loosening at the interface between bone and the cement. One of the requirement...
Saved in:
Main Author: | |
---|---|
Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/10220 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Institut Teknologi Bandung |
Language: | Indonesia |
Summary: | Polymethylmethacrylate (PMMA)-based bone cement is one of the most popular materials for implant fixations. These bone cement have limitations, one of them is they do not show bone-bonding characteristic which caused bond loosening at the interface between bone and the cement. One of the requirements for a biomaterial to have bone-bonding characteristic is the formation of bioactive layer. Bioactive layer, such as apatite layer, will be formed on biomaterial's surface when implanted in human body. Formation of this layer can be observed on bioactive material when it was soaked inside Kokubo solution (Simulated Body Fluid). Kokubo Solution has ion concentrations nearly equal to human blood plasma. The previous researches revealed that the formation of apatite layer is initiated by the Ca2+ ions release from material to the body fluid. Catalytic effect of Si-OH groups formed on the surface of the material will accelerate the formation of apatite layer. Based on previous researches, PMMAbased bone cement will be modified by adding 20% mass of calcium salt to powder component. In this research Tetraethylorthosilicate (TEOS) was added to liquid component. The results show that modification with TEOS and Calcium salt, with higher water-solubility, is effective to create PMMA-based bone cement with bonebonding characteristic. Considering TEOS price and availability as modifier, we can get better bone cement with more affordable price. In the future, we need more research to get more information about this modified bone cement properties. |
---|