IDENTIFICATION OF REGION B AND C DNA FRAGMENT MUTATION ON REVERSE TRANSCRIPTASE DOMAIN AND CLONING OF OPEN READING FRAME ENCODING POLYMERASE OF HEPATITIS B VIRUS IN ESCHERICHIA COLI JM109
Antiviral treatment effectively suppressing the viral replication of hepatitis B virus (HBV). Yet, drug resistant mutants arise with increased length of treatment. Some mutations have been investigated at reverse transcriptase (RT) domain, more specific in region B and C which were suggested to be r...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/10618 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |