#TITLE_ALTERNATIVE#
There are so many potential effects that green tea has, such as antibacterial activity against Propionibacterium acnes, bacteria that caused acne. That effect had been studied and already made in gel. In this study, formula of green tea water extract gel is developed with addition of antioxidant so...
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| Format: | Final Project |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/11020 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | There are so many potential effects that green tea has, such as antibacterial activity against Propionibacterium acnes, bacteria that caused acne. That effect had been studied and already made in gel. In this study, formula of green tea water extract gel is developed with addition of antioxidant so that the stability of gel would increase. Gel of green tea water extract were made using Carbopol 940 with glycerin as the solvent. The chosen antioxidant was sodium sulfite. It is also combined with chelating agent, EDTA (Edetic Acid). The activity of green tea water extract gel were determined and tetracycline HCl gel was used as the reference. The addition of sodium sulfite 1% w/w into gel with Carbopol 940 1% w/w as the base prevent the color changed more than eight weeks. Minimum Inhibitory Concentration (MIC) of green tea water extract without either sodium sulfite or EDTA was 1,20+0,11 cm. MIC of green tea water extract with addition of sodium sulfite 1% w/w was 1,19+0,28 cm. MIC of green tea water extract with addition of sodium sulfite 1% w/w and EDTA 0,1% w/w was 1,25+0,22 cm. The addition of sodium sulfite 1% w/w caused viscosity of gel decrease 42,1%. The addition of sodium sulfite 1% w/w increased the color stability of green tea water extract. The addition of sodium sulfite 1% w/w didn't decrease its antibacterial activity against Propionibacterium acnes. <br />
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