Poilaneic Acid from the Leafs of Macaranga pruinose

• Main Author: MAHENDRA (NIM 10502021), HARITS
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/12179
• Institution: Institut Teknologi Bandung

Macaranga is one of genus from Euphorbiaceace familia. Macaranga plant wide spread in numerous numbers, for more than 300 species through out North Africa, Madagascar, Australia, Asia, and South Pacific. In Indonesia Macaranga covers Borneo, South Sumatra, and Sulawesi’s tropical rain forest ecosystem. Macaranga known to mutuality symbiotic with ants (especially Cromatogasters and subgenus Decacrema). In myrmekofitism facultative interaction, these plants provide food through its twig, and flowers for ant, and in return ant protected it from the attack of herbivores insect. Traditionally, Macaranga are commonly used for the purposed of building material, such as pole/column, or roofing, and for traditional medication. In this experiment, the isolations of the leaves part of the Macaranga pruinosa has been conducted through extraction with methanol liquefiers, and continued with Liquid Vacuum Chromatography fractionation and Radial Chromatographic with n-hexane and EtOAC liquefier. It has been separated successfully one valid pure compound, in form of tick colorless liquid. The structural elucidation result with spectroscope C-13 NMR and H-1 NMR showed this compound Diterpen Monocyclic is Cembrane derivative which is Poilaneic Acid. <br />