DETERMINATION AND STUDY OF ZN(II), CU(II), CD(II) AND NI(II) ACCUMULATIONS IN BLOOD SERUM OF LABORATORY RATS, PREVIOUSLY ORALLY FED WITH GREEN MUSSELS (PERNA VIRIDIS)

• Main Author: YUDHISTIRA AZIS (NIM 10504046), MUHAMMAD
• Format: Final Project
• Language: Indonesia
• Subjects: Kimia
• Online Access: https://digilib.itb.ac.id/gdl/view/12433
• Institution: Institut Teknologi Bandung

Green Mussel (Perna viridis) is a well-known living organism in deep-sea sediments, playing role as bio-indicator or biomonitoring agent for heavy-metal contaminations in the sea. In this research, Zn(II), Cu(II), Cd(II) and Ni(II) concentrations, in green mussels from sea body water in Mundu, Cirebon, were determined. Determination of such heavy-metal cations was carried out by Atomic Absorption Spectrophotometry (AAS), applied to dry digested samples. Analytical performance was evaluated by determining % recovery for artificial samples. Meanwhile, for real samples of green mussels, evaluation was realized by determining confidence limit for the obtained results. The result showed that there was a sequence of heavy-metal cations content in green mussels sample, such as Ni(II) < Cd(II) < Cu(II) < Zn (II). In this research, the possibility of accumulation of heavy-metal cations in blood serum of laboratory rats, previously orally fed with green mussels for certain periods of time, i.e. for 4, 8 and 12 days was explored. Determination of heavy-metal cations in blood serum of laboratory rats revealed the evidence of heavy-metal cations accumulations, such as Zn(II), Cu(II), and Cd(II) for any categories of laboratory rats.