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Watermelon fruit has traditional use as treatment for kidney stones. Publication of chemical content of watermelon fruit is limited. The goal of the research is to study the chemical content of white part of watermelon fruit. Crude drug of watermelon fruit were consequtively extracted by maseration...

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Bibliographic Details
Main Author: LISTIANE (NIM 10704013); Pembimbing: Dr. Irda Fidrianny dan Dra. Siti Kusmardiyani, M.Sc., SHINTA
Format: Final Project
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/13836
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Institution: Institut Teknologi Bandung
Language: Indonesia
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Summary:Watermelon fruit has traditional use as treatment for kidney stones. Publication of chemical content of watermelon fruit is limited. The goal of the research is to study the chemical content of white part of watermelon fruit. Crude drug of watermelon fruit were consequtively extracted by maseration using n-hexane, ethyl acetate and ethanol. Ethyl acetate extract was fractionated with liquid-liquid extraction using n-hexane and methanol-water. Purification was conducted by preparative thin layer chromatography. Characterization isolate was performed by using ultraviolet-visible spectrophotometry and infrared spectrophotometry. Crude drug of white part of watermelon fruit showed the presence of flavonoid and steroid/triterpenoid compounds. Isolate A had been isolated from ethyl acetate extract. Isolat A was supposed to be a triterpenoid that has OH, C=O, C=C and CH aliphatic groups without any conjugated double bond. <br />