SENYAWA OLIGOMER STILBEN DARI KULIT BATANG SHOREA LEPROSULA MIQ.

• Main Author: Nyoman Adiwinata, I
• Format: Theses
• Language: Indonesia
• Subjects: Kimia
• Online Access: https://digilib.itb.ac.id/gdl/view/2104
• Institution: Institut Teknologi Bandung

Four oligomer stilbenes, hemsleyanol D, hopeaphenol, laevifonol, and (+)-a-viniferin had been isolated from acetone extract of the stem bark of Shorea leprosula Miq. The molecular structures of these compounds were determined based on spectroscopic data, including mass spectroscopic, UV, IR, 1-D NMR, and 2-D NMR, as well as by comparison to that reported in the literature. (+)-a.-Viniferin showed cytotoxic activity againts brine shrimp Artemia sauna with LC50 47,7 µg/ml, while other compouds were not active. The finding of hemsleyanol D, laevifonol, and (+)-a-viniferin in S. leprosula were very important, because of a rare of their occurrence in the genus Shorea. Furthermore, the presence of hopeaphenol in this plant supported a hyphotesis that the compound is a chemotaxonomic marker of Dipterocarpaceae.