PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN
Rice field rat (Rattus argentiventer) has high reproductive capacity. It is known that a-chlorohydrin could effectively decrease the fertility of certain male animals, but information on the rice field rat is not present. The aim of this experiment is to analyze the influence of achlorohydrin on the...
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id-itb.:21272004-10-25T16:56:36ZPENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN TRIANTY, LEILY Ilmu hayati ; Biologi Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/2127 Rice field rat (Rattus argentiventer) has high reproductive capacity. It is known that a-chlorohydrin could effectively decrease the fertility of certain male animals, but information on the rice field rat is not present. The aim of this experiment is to analyze the influence of achlorohydrin on the reproductive capacity of male rice field rat with special reference on the fertility and the function of the reproductive organs. A single dose of 90 mg/kg b.w. of achlorohydrin was administered by gavage. The results revealed that a-chlorohydrin decrease significantly the quality of caudal epididymal sperm and the fertility of the male rat within 2 – 48 days after treatment. The infertility persisted throughout 48 days after treatment, but the reproductive capacity regained at 29. days after treatment. The reduction of the sperm quality appeared to be caused by development of lesions on the epididymal and testicular tissues. Lesion which could detected on the epididymal ducts were epithelial degeneration, increase in lumen diameter, the absent of sperms in the lumen and in the testicular tissues were edema of the interstitial tissues and atrophy of the seminiferous tubules. The worst damage occurred at 14 days after treatment. On the other hand, a change in the protein profile of epididymal fluid also occurred after achlorohydrin treatment, which could have an influence on the quality of the sperm. It could be concluded that a-chlorohydrin reduce the reproductive capacity of male rice field rat (Rattus argentiventer) within 2 to 48 days. text |
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Ilmu hayati ; Biologi TRIANTY, LEILY PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
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Rice field rat (Rattus argentiventer) has high reproductive capacity. It is known that a-chlorohydrin could effectively decrease the fertility of certain male animals, but information on the rice field rat is not present. The aim of this experiment is to analyze the influence of achlorohydrin on the reproductive capacity of male rice field rat with special reference on the fertility and the function of the reproductive organs. A single dose of 90 mg/kg b.w. of achlorohydrin was administered by gavage. The results revealed that a-chlorohydrin decrease significantly the quality of caudal epididymal sperm and the fertility of the male rat within 2 – 48 days after treatment. The infertility persisted throughout 48 days after treatment, but the reproductive capacity regained at 29. days after treatment. The reduction of the sperm quality appeared to be caused by development of lesions on the epididymal and testicular tissues. Lesion which could detected on the epididymal ducts were epithelial degeneration, increase in lumen diameter, the absent of sperms in the lumen and in the testicular tissues were edema of the interstitial tissues and atrophy of the seminiferous tubules. The worst damage occurred at 14 days after treatment. On the other hand, a change in the protein profile of epididymal fluid also occurred after achlorohydrin treatment, which could have an influence on the quality of the sperm. It could be concluded that a-chlorohydrin reduce the reproductive capacity of male rice field rat (Rattus argentiventer) within 2 to 48 days. |
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Theses |
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TRIANTY, LEILY |
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TRIANTY, LEILY |
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TRIANTY, LEILY |
title |
PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
title_short |
PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
title_full |
PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
title_fullStr |
PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
title_full_unstemmed |
PENGARUH A-KLOROHIDRIN TERHADAP KEMAMPUAN REPRODUKSI TIKUS SAWAH (RATTUS ARGENTIVENTER) JANTAN |
title_sort |
pengaruh a-klorohidrin terhadap kemampuan reproduksi tikus sawah (rattus argentiventer) jantan |
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https://digilib.itb.ac.id/gdl/view/2127 |
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