TRANSFORMASI HIPTOLIDA
Hyptis pectinata Poit is one of the plat of the Labiateae family, which is easily found and grows in the area where there is enough sun shine. From the chemical aspects, Hyptis pectinata was investigated first time by Gorter in 1920, who found hyptolide a bitter compound, from the leaves of this pla...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/2147 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Hyptis pectinata Poit is one of the plat of the Labiateae family, which is easily found and grows in the area where there is enough sun shine. From the chemical aspects, Hyptis pectinata was investigated first time by Gorter in 1920, who found hyptolide a bitter compound, from the leaves of this plant. Structure of hyptolide which was suggested by Gorter, had been reinvestigated by Birch and Butler ( 1964), and completed by S.A. Achmad (1987). Considering that hyptolida may be obtained in high yield (± 2 %), thus, it may be used as a starting material for synthe - tic studies. Hyptolida was isolated, melting point : 87-88 °C, Rf = 0,82 (CHC13), and the structure was confir firmed by spectroscopic methods, uv, IR, MS and NMR. Epoxidation of hyptolide with m-chloroperben - zoic acid in chloroform yield a solid product (60 %), melting point : 75 - 76 °C, Rf = 0,21 (CHC13), 1l max = 224,5 nm (ethanol), gave indications that the was still present the(rumus) unsaturated lacton system. The mass spectrum of the epoxidation product showed peaks at |
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