#TITLE_ALTERNATIVE#

• Main Author: SILVYA DEVI NIM : 11614036, MELATI
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/28847
• Institution: Institut Teknologi Bandung

Cigarette smoking is common among Indonesian. Exposure to cigarette smoke can have effect on the <br /> <br /> body’s endurance, cognitive function, and organs histology of the active and passive smokers. This <br /> <br /> research was design to analyze the effect of exposure to conventional cigarette smoke and electric <br /> <br /> cigarette smoke on performance in forced swimming test, cognitive function and organs histology, <br /> <br /> having forced swimming test (FST), Y-maze method, and organ index calculation. This study was <br /> <br /> conducted in 3 groups of mice, which were control group (not exposed to smoke), mice group exposed <br /> <br /> to conventional cigarette smoke (1.5 mg of nicotine or one stick per day), and mice group exposed to <br /> <br /> electric cigarette smoke (1.5 mg of nicotine or 0.5 mL per day). Exposure to cigarette smoke in mice <br /> <br /> lasted for 13 days. The FST was performed on days 0, 2, 4, 6, 8, 10, 12, and 13. While the Y-maze <br /> <br /> method test was performed the day before the FST, on days 1, 3, 5, 7, 9, 11, and 13. On day 14, all <br /> <br /> mice were ex amined for organ index by weighing the lungs, heart, kidneys, liver, spleen, testes, <br /> <br /> seminal vesicles, and brain. The results showed that the group of mice exposed to cigarette smoke <br /> <br /> tests (conventional cigarette and electric cigarette) for 13 days demonstrated decreased swimming <br /> <br /> ability with significant difference (p <0.05) from control group. In testing of cognitive function with Ymaze method, increased cognitive ability in all test groups after 13 days of treatment was observed. <br /> <br /> Cigarette smoke exposure for 13 caused significant deacrease (p<0.05) in lung index compared to <br /> <br /> control. <br />