#TITLE_ALTERNATIVE#

• Main Author: HANIF AT-THARIF NIM : 10714044, NAUFAL
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/29576
• Institution: Institut Teknologi Bandung

Jawer kotok leaves (Plectranthus scutellarioides (L.) R.Br., Lamiaceae) traditionally used for treatment of <br /> <br /> hemorrhoid, diabetes, fever, diarrhea, late menstruation and abscess. Researches and publications <br /> <br /> regarding the chemical compounds of jawer kotok leaves were still limited, so the aim of this research was <br /> <br /> to isolate the main flavonoid compound of jawer kotok leaves (Plectranthus scutellarioides (L.) R.Br.) <br /> <br /> obtained from Botanical Garden Manoko, Lembang, West Bandung. The crude drug of jawer kotok leaves <br /> <br /> was extracted by maceration using 70% ethanol. Furthermore, ethanol extract was concentrated, added <br /> <br /> with some hot water and filtered before being fractionated by liquid-liquid extraction using n-hexane and <br /> <br /> ethyl acetate solvent respectively. Based on the monitoring of the chromatogram pattern, the water <br /> <br /> fraction was chosen for separation and purification process using preparative paper chromatography. The <br /> <br /> characterization of isolate was carried out using UV-visible spectrophotometery with several reagents. The <br /> <br /> isolate obtained has absorption peaks at 268 nm and 328 nm which was suspected to be flavone groups <br /> <br /> with 4’-OH. <br />