ORGANOCHLORINE INSECTICIDE EXPOSURE EFFECT TO CHANGING SPRAYING FARMERS’S THYROID STIMULATING HORMONE (TSH) LEVEL IN KERTASARI DISTRICT, BANDUNG REGENCY

• Main Author: MAULIDINIAWATI , NURIKA
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/29791
• Institution: Institut Teknologi Bandung

<p align="justify">The use of insecticides in agriculture is now often done by farmers to achieve <br /> <br /> <br /> <br /> sustainable agriculture against insect pests. One insecticide widely used in Indonesia is a class of organochlorine insecticides. Organochlorine insecticides are persistent both in the environment and in the bodies of living things are exposed. Long term exposure to organochlorine insecticides will have an impact on the health changes on sprayer farmers, one of which is a thyroid disorder in the form of increasing level of Thyroid Stimulating Hormone (TSH). This research was conducted on spraying farmers in Kertasari district, Bandung regency. Sampling was taken when farmers do insecticide spraying activity using pad sampling to check dermal exposure. This report describes <br /> <br /> organochlorine concentration which exposes spraying farmers and then converted to the accumulation of the intake to see the effect to TSH level in farmer’s blood. This paper also described the factors that can affect TSH levels in the farmer’s blood and the risk value between exposed farmer and unexposed farmer. Organochlorine insecticides that were detected in the field, namely lindane, heptachlor, aldrin, endosulfan, DDT, dieldrin, and endrin, with each highest value of exposures were 0,7818 mg/cm², 0,021 mg/cm², 0,5824 mg/cm², 0,0464 mg/cm², 0,0025 mg/cm², 0,0014 <br /> <br /> mg/cm², and 0,1108 mg/cm². The results of statistical tests indicate there is a relationship between exposure with intake and the increasing of TSH level which the factor has a strong relationship was lindane intake (Pearson correlation. r=0.656, p=0.000). The risk value also showed that exposed farmer has higher risk to get Hypothyroid disease than unexposed farmer.<p align="justify">