#TITLE_ALTERNATIVE#

• Main Author: A’YUN NIM : 11614007, QURROTA
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/30068
• Institution: Institut Teknologi Bandung

Acute Respiratory Infection (ARI) is one of the main causes of patient visits in Community Health <br /> <br /> Center (Puskesmas) (40%-60%) and hospitals (15%-30%). Pharyngitis is an inflammation of the <br /> <br /> pharyngeal wall caused by viruses (40%-60%) and bacteria (5%-40%). ARI stewardship program <br /> <br /> specifically aims to reduce morbidity and mortality, especially in infants and toddlers, however the <br /> <br /> morbidity and mortality rates are still high as reported in the Result of Basic Health Research of <br /> <br /> 2013. This study aimed to compare two methods of identifying the causes of acute pharyngitis using <br /> <br /> Centor Criteria and analysis of symptoms, signs and comorbidities, evaluate the rationality of <br /> <br /> antibiotic use; identify the impact of irrationality; and see if there was any relationship between <br /> <br /> patient adherence and the outcome of therapy of acute pharyngitis patients. This was a descriptive <br /> <br /> observational study involving evaluation the rational use of medicine, carried out retrospectively <br /> <br /> and concurrently at the Community Health Center (Puskesmas) Ciumbuleuit, Bandung in the period <br /> <br /> of March-June 2018. The results of the identification of causes of acute pharyngitis in both <br /> <br /> retrospective and concurrent phases showed no significant differences whether the evaluation was <br /> <br /> based on the Centor Score method or the method of analysis of symptoms, signs, and comorbidities <br /> <br /> (p = 0.830 and p = 0.593). In the retrospective phase, there were 59.55% of patients received <br /> <br /> antibiotic therapy albeit only an average of 27.7% of patients who were indicated to receive <br /> <br /> antibiotics. In the concurrent phase, the rationality of antibiotic use comprised the accuracy of the <br /> <br /> indication (46.67%), the accuracy of drug selection (87.5%), and the accuracy of the dose (100%), <br /> <br /> but there was inaccuracy in duration of antibiotic given to almost all patients. The results of <br /> <br /> therapeutic outcomes showed that 73.33% patients received good therapeutic results, with <br /> <br /> antibiotics and without antibiotics. The condition of patients with persistent symptoms after <br /> &#278;¨®¨ç&#330;ç&#256;Ú  &#256;&#292;ç­ç&#263;&#292;ç®&#282;&#331; &#282;&#292;ä&#263;&#319;Úä&#292;&#292;&#263;­¨ ¸&#319;¨ &#292;&#263;&#275; &#292;ç¨&#256;&#292;&#1049435;&#282;&#256;&#263;&#256;-compliance (26.67%). The irrationality <br /> <br /> of antibiotic use could have an impact on the emergence of bacterial resistance to antibiotics and <br /> <br /> the increased risk of side effects in patients. <br />