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Bacteria and fungi that grow in the mouth can cause oral infections, and may include bad breath, <br /> <br /> dental caries, and candidiasis, etc. Cinnamomum zeylanicum or True Cinnamon had showed <br /> <br /> antibacterial activity against some oral bacteria on the previou...
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| Format: | Final Project |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/30260 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Bacteria and fungi that grow in the mouth can cause oral infections, and may include bad breath, <br />
<br />
dental caries, and candidiasis, etc. Cinnamomum zeylanicum or True Cinnamon had showed <br />
<br />
antibacterial activity against some oral bacteria on the previous studies, but there is no comparison <br />
<br />
between antimicrobial activity of Cinnamon bark in powdered bark and bark stick. The aim of this <br />
<br />
study was to determine the antimicrobial activity of Cinnamomum zeylanicum acetonic bark extract <br />
<br />
using bark stick and powdered bark on some oral cavity pathogens. The crude drug was extracted by <br />
<br />
cold maceration method using acetone as solvent. Both extracts were tested for antimicrobial activity <br />
<br />
using disc diffusion method or Kirby-Bauer test against Enterococcus faecalis, Streptococcus mutans, <br />
<br />
Staphylococcus aureus ATCC 6538, and Candida albicans ATCC 10231. Kirby-Bauer test showed that <br />
<br />
bark stick extract having greatest antimicrobial activity against Candida albicans with diameter 34.63 <br />
<br />
mm for concentration 800 mg/mL of the extract . The smallest inhibition by bark stick extract was <br />
<br />
Staphylococcus aureus with diameter 10.15 mm for concentration 800 mg/ml of the extract. Powdered <br />
<br />
bark extract also having greatest antimicrobial activity against Candida albicans with diameter 23.70 <br />
<br />
mm for concentration 800mg/mL of the extract. The smallest antimicrobial activity by powdered bark <br />
<br />
extract was Streptococcus mutans with diameter 9.90 mm for concentration 800 mg/mL of extract. <br />
<br />
The bark stick extract showed that it have greater inhibition compared to powdered bark extract <br />
<br />
against Candida albicans. Both cinnamon bark extract gave best inhibition against Candida albicans <br />
<br />
compared to other oral bacteria. <br />
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