#TITLE_ALTERNATIVE#

• Main Author: HARDIANTI PUTRI NIM : 11614028, UTAMI
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/31423
• Institution: Institut Teknologi Bandung

Cesarean delivery is a surgical procedure by making incisions through abdominal wall and uterus to deliver <br /> <br /> the baby. Surgical Site Infection (SSI) is one of the complications that can prolong postoperative length of <br /> <br /> stay, including in cesarean section patients. Based on several studies, the use of prophylactic antibiotics <br /> <br /> can reduce the risk of SSI events. There are several risk factors for SSI events, one of which is the <br /> <br /> incompatibility of surgical prophylactic antibiotics. In 2017, in one hospital of Bandung, there was an SSI <br /> <br /> incident in patients after cesarean section. The preliminary study shows there are discrepancies in doses <br /> <br /> and the timing of prophylactic antibiotics with Standard Operating Procedure (SOP) and the latest <br /> <br /> recommendations from American Society of Health-System Pharmacist (ASHP). Recommended <br /> <br /> prophylactic antibiotic dose is 2 g which is given within 60 minutes before incision. The study was <br /> <br /> conducted to analyze the effect of dose and surgical prophylactic antibiotic administration timing on the <br /> <br /> incidence of SSI in patients undergoing cesarean section, effect of other risk factors, and effect of ILO on <br /> <br /> postoperative length of stay. Descriptive and analytic observational studies were conducted <br /> <br /> retrospectively from medical record data in 2017. The samples included in the data analysis were 290 <br /> <br /> patients with 12 of them experiencing SSI after cesarean section. Based on the results of the bivariate chisquare analysis, dose (p&#8805;0,05) and prophylactic antibiotic administration timing (p&#8805;0,05; OR: 1,53; 95% <br /> <br /> CI: 0,48-4,86) do not affect the incidence of SSI in patients after cesarean section. Based on logistic <br /> <br /> regression analysis, obesity as other risk factor significantly affected the incidence of SSI (p<0,05; OR: 3,71; <br /> <br /> 95% CI: 1,05-12,50). SSI significantly affected the postoperative length of stay (p<0,05). <br />