MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL

Paracetamol is an analgesic that’s useful in broad range of clinical condition. however, at higher doses it can produce NAPQI which causing acute hepatic necrosis. Therefore it is very important to develop effective analytical methods for paracetamol analysis. One of that methods is voltammetry wi...

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Main Author:	Hafidhoh S N, Sanny
Format:	Final Project
Language:	Indonesia
Subjects:	Kimia
Online Access:	https://digilib.itb.ac.id/gdl/view/36182
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Institution:	Institut Teknologi Bandung
Language:	Indonesia

id	id-itb.:36182
spelling	id-itb.:361822019-03-08T15:05:33ZMODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL Hafidhoh S N, Sanny Kimia Indonesia Final Project molecularly imprinted poly(glutamic acid), non imprinted polymer, paracetamol, voltammetry INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/36182 Paracetamol is an analgesic that’s useful in broad range of clinical condition. however, at higher doses it can produce NAPQI which causing acute hepatic necrosis. Therefore it is very important to develop effective analytical methods for paracetamol analysis. One of that methods is voltammetry with carbón paste electrode (CPE) as working electrode. However, CPE gives low current response. CPE modification with NIP (non imprinted polymer) technique and MIP (molecularly imprinted poly(glutamic acid)) technique can increase current response. Modification occured with cyclic voltammetry and determination of paracetamol occured with differential pulse voltammetry. Paracetamol determination with CPK -NIP- MIP (monomer:template composition = 3:1) gives increasing peak current. %RSD of repeated detemination is 13,72% (n=40). The calibration curve at range 100-1000 ?M was the most linear (limit of detection = 2,16 ?M). Result of paracetamol sample determination with CPE-NIP-MIP showed %recovery close to 100%. text
institution	Institut Teknologi Bandung
building	Institut Teknologi Bandung Library
continent	Asia
country	Indonesia Indonesia
content_provider	Institut Teknologi Bandung
collection	Digital ITB
language	Indonesia
topic	Kimia
spellingShingle	Kimia Hafidhoh S N, Sanny MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
description	Paracetamol is an analgesic that’s useful in broad range of clinical condition. however, at higher doses it can produce NAPQI which causing acute hepatic necrosis. Therefore it is very important to develop effective analytical methods for paracetamol analysis. One of that methods is voltammetry with carbón paste electrode (CPE) as working electrode. However, CPE gives low current response. CPE modification with NIP (non imprinted polymer) technique and MIP (molecularly imprinted poly(glutamic acid)) technique can increase current response. Modification occured with cyclic voltammetry and determination of paracetamol occured with differential pulse voltammetry. Paracetamol determination with CPK -NIP- MIP (monomer:template composition = 3:1) gives increasing peak current. %RSD of repeated detemination is 13,72% (n=40). The calibration curve at range 100-1000 ?M was the most linear (limit of detection = 2,16 ?M). Result of paracetamol sample determination with CPE-NIP-MIP showed %recovery close to 100%.
format	Final Project
author	Hafidhoh S N, Sanny
author_facet	Hafidhoh S N, Sanny
author_sort	Hafidhoh S N, Sanny
title	MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
title_short	MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
title_full	MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
title_fullStr	MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
title_full_unstemmed	MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL
title_sort	modification of carbon paste electrode with non imprinted polymer and molecularly imprinted poly(glutamic acid) for voltammetric determination of paracetamol
url	https://digilib.itb.ac.id/gdl/view/36182
_version_	1821997082145193984

MODIFICATION OF CARBON PASTE ELECTRODE WITH NON IMPRINTED POLYMER AND MOLECULARLY IMPRINTED POLY(GLUTAMIC ACID) FOR VOLTAMMETRIC DETERMINATION OF PARACETAMOL

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