QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP OF BIPHENYLUREA DERIVATIVES AS INHIBITOR OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2
Biphenylurea derivatives can be used as tyrosine-kinase inhibitors (TKI). Tyrosine kinase is an enzyme which has a role of activation of signal transduction cascades of various proteins. TKI inhibits the phosphorylation of activated proteins. The activation of vascular endothelial growth factor re...
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Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/36990 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |