MOLECULARLY IMPRINTED POLYMER AS SELECTIVE FUNCTIONAL MATERIAL FOR SEPARATION ALPHA-TOCOPHEROL WITH BATCH METHODE
Molecularly Imprinted Polymer (MIP) is a polymer made of templates or analytes synthesized by polymerization principle using templates, functional monomers, crosslinkers, initiators and solvents. MIP is used as an adsorbent of extraction and purification processes of a-tocopherols from various...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses |
| Language: | Indonesia |
| Subjects: | |
| Online Access: | https://digilib.itb.ac.id/gdl/view/38615 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Molecularly Imprinted Polymer (MIP) is a polymer made of templates or analytes synthesized by polymerization principle using templates, functional monomers, crosslinkers, initiators and solvents. MIP is used as an adsorbent of extraction and purification processes of a-tocopherols from various plant samples, oils, and drugs. MJP is very important in analytical chemistry to produce a good accuracy, precision, sensitivity and selectivity of an analysis. In this study, MIP was used for adsorbing a-tocopherol and Non-Imprinted Polymer (NIP) was used as a comparison. MIP was synthesized using a-tocopherol as a template. Methaacrylic Acid as a monomer, ethylen glycol di methaacrylic as a crossUnker, benzoyl peroxide as the initiator, chloroform as porogen and polymerized using a
microwave for 14.5 minutes at 50 oc and stirred at 420 rpm.The characterization
of FnR showed that there are several important peaks in the fmgerprint region originating from long alkyl a-tocopherol chains. SEM analysis showed that surface morphology of MIP without leaching is rougher than NIP and MrP. TGA analysis illustrated that MlP has higher thermal stability than NIP. The adsorption kinetics model is the of pseudo ho second orde while the isotherm adsorption model is Langmuir. MIP has 17.4 mg/g adsorption capacity, 43 minutes contact time, and pre-concentration can be conducted for four times. MIP is more selective for a-tocopherols than 2.5 ditertsier butyl hydroquinon as a comparative compound. The percentage of recovery from antioxidant activity showed that a tocopherol did not degrade during the adsorption and desorption processes and it was still active in inhibiting 2.2-diphenyl-1-picrylhydrazyl free radicals. Drug analysis using MLP produced 96.53% recovery percentage.
|
|---|