CoBTC Based Metal Organic Framework (MOF) Synthesis as an Electrochemical Biosensor for Glucose Detection

• Main Author: Ayub Aritonang, Robitson
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/39645
• Institution: Institut Teknologi Bandung

Diabetes mellitus is one of the highest causes of death in the world caused by high levels of glucose in the blood. Thus, controlling glucose levels in the blood becomes very important. Non-enzymatic glucose detection is currently a hot topic, one of which is to use Metal Organic Material (MOF) which has advantages such as having a large surface area and having a large amount of micropore. The purpose of this study was to synthesize MOF CoBTC and see its performance as a glucose sensor. The synthesis method used is the solvothermal method, while the sensor performance testing method uses an electrochemical method. Solvothermal CoBTC was carried out at temperature variations of 85°C, 100°C, 115°C and 100°C and variations in duration of synthesis of 10 and 20 hours. The best performance were obtained on CoBTC material with a temperature 100°C and duration of synthesis 10 hours, respectively. CoBTC materials then further characterized using X-Ray Diffraction (XRD), Scanning Elektron Microscopy (SEM), Fourier Transform Infrared (FTIR) Spectroscopy, Brunauer Emmett Teller (BET) Surface Area Analyzer. The electrochemical test results showed the optimal working potential of the sensor at 0,4 V, sensitivity of 53,455 ?A mM-1 cm-2 with a detection limit of 5,49 ?M, and detection linearity of 98%. With this result, sensors are considered to have met the standards of the Food and Drug Association (FDA) with a minimum accuracy of 95% to use as a glucose sensor.