THE INCORPORATION EFFECT OF CHLORHEXIDINE AND CETYL TRIMETHYL AMMONIUM BROMIDE ON MECHANICAL PROPERTIES AND ANTIBACTERIAL ACTIVITY OF DENTAL RESTORATIVE NANOCOMPOSITE

• Main Author: Widiantoro, Cahyo
• Format: Final Project
• Language: Indonesia
• Subjects: Teknik (Rekayasa, enjinering dan kegiatan berkaitan)
• Online Access: https://digilib.itb.ac.id/gdl/view/39663
• Institution: Institut Teknologi Bandung

The prevalence of dental caries among the Indonesian population is about 72.6%. Resin composite can be used to remedy dental caries. However, during application, resin composites has limited lifetime due to premature cracking and secondary caries disease. The direct incorporation of antibacterial agent into resin can improve physical and mechanical properties of composite. Antibacterial encapsulation using porous-silica nanoparticles (PSNs) will enhance both mechanical and antibacterial properties respectively. PSNs is synthesized according to references and characterized. Chlorhexidine (CHX) and Cetyltrimethylammonium Bromide (CTAB) are used as the antibacterial agent. The test samples are prepared by varying of CHX and CTAB as follows: 0% (control); 0.6% CHX; 0.6% CTAB; 1.5% CTAB; and 3.0% CTAB (w/w). Mechanical properties are tested using hardness and bending test. The antibacterial activity is tested using agar diffusion test and agar dilution test. The experimental result show that CTAB antibacterial encapsulation using PSNs will improve surface hardness, maintain flexural strength, increase flexural stiffness, and substantially hampers antibacterial diffusion rates. In this research, it is proven that antibacterial encapsulation with PSNs can maintain mechanical properties and improve the antibacterial durability.