COMPUTATIONAL MODELING OF INCLUSION COMPLEX OF (R/S)-IBUPROFEN WITH Ã-CYCLODEXTRIN AND ITS DERIVATIVES
Chiral separation is an important subject in analytical clinical chemistry, because of differences in the biological activity and pharmacokinetic properties of drug enansiomers. Ibuprofen, R,S-2-(4-isobutylphenyl)propionic acid, a derivative of 2-arylpropionic acids (profens), is a chiral non-steroi...
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Format: | Dissertations |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/42233 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |