COMPUTATIONAL MODELING OF INCLUSION COMPLEX OF (R/S)-IBUPROFEN WITH ß-CYCLODEXTRIN AND ITS DERIVATIVES

Chiral separation is an important subject in analytical clinical chemistry, because of differences in the biological activity and pharmacokinetic properties of drug enansiomers. Ibuprofen, R,S-2-(4-isobutylphenyl)propionic acid, a derivative of 2-arylpropionic acids (profens), is a chiral non-steroi...

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Bibliographic Details
Main Author: Siti Nurhidayah, Enung
Format: Dissertations
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/42233
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Institution: Institut Teknologi Bandung
Language: Indonesia