PENGEMBANGAN NANOSPONGE ATORVASTATIN KALSIUM BASIS ?-SIKLODEKSTRIN
Atorvastatin calcium (AC) is a BCS (biopharmaceutical classification system) class II drug which belongs to statin drug group (first line in dyslipidemia treatment). AC has poor aqueous solubility (0,8 mg/mL at 37 °C), high permeability at physiological pH of intestine (6–6,5), and low bioavailab...
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Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/44117 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |