PENGEMBANGAN NANOSPONGE ATORVASTATIN KALSIUM BASIS ?-SIKLODEKSTRIN

Atorvastatin calcium (AC) is a BCS (biopharmaceutical classification system) class II drug which belongs to statin drug group (first line in dyslipidemia treatment). AC has poor aqueous solubility (0,8 mg/mL at 37 °C), high permeability at physiological pH of intestine (6–6,5), and low bioavailab...

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Bibliographic Details
Main Author: Vania Boru Tobing, Ayu
Format: Final Project
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/44117
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Institution: Institut Teknologi Bandung
Language: Indonesia