Drug Use Review and Monitoring the Effectiveness of Antihypertensive Therapy at Health Care Center Bumi Medika Ganesha – Institut Teknologi Bandung

• Main Author: Nadhira Qinthari, Siti
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/45550
• Institution: Institut Teknologi Bandung

Hypertension still became a serious problem in Indonesia because it is the most cause of death disease in Indonesia. Due to the data in Indonesian Society of Hypertension (InaSH), death caused by hypertension from 2000 – 2013 reached 7 millions deaths out of 56 millions deaths. In 2013, West Java was the third province with highest prevalence of hypertension disease in Indonesia. Treatment of hypertension has been internationally standardized in accordance to Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). The aim of hypertension standard therapy is to control a normal blood pressure and prevent organ damage. Bandung Institute Technology (ITB) has a health care center (BMG) providing hypertension therapy out of other several health problems. Drug-use evaluation of antihypertensive drugs and monitoring of hypertension therapy effectiveness in BMG, currently, has not yet conducted regularly which could disturb the hypertension therapy if it does not take in good care. Therefore, this research was designed to evaluate the appropriateness/inappropriateness of antihypertensive drug-use and monitor the effectiveness of hypertension therapy. This research is a descriptive-observational study consists of antihypertensive drug-use evaluation based on predetermined criteria that generated from the current literature and monitor the effectiveness therapy of hypertension by direct interview to the patients. In antihypertensive drug-use evaluation study, from 74 patients (45 men and 29 women) about 17 inappropriate medication-use cases were found consisted of 13 cases (76,47%) of inappropriate drugselection, 1 case (5,88%) of inappropriate dose-selection (high dose), and 3 cases (17.67%) of drug interactions with the average total of inappropriate case for each patient are 2 inappropriate cases. From hypertension therapy effectiveness monitoring, approximately 19 patients with a complete blood pressure records in medical record were recruited to conduct the interview. There are 4 patient (21,05%) achieved blood pressure target and 15 patients (78,95%) did not achieved blood pressure target. The contributing factors to ineffectiveness therapy were Body Mass Index (BMI) more than 24,9 kg/m 2 from 9 patients (60%), patient’s daily habit by smoking habit, coffee or tea consumption also lack of physical activity or exercises from 8 patients (53,33%), and non-adherence consumption behavior from 8 patients (53,33%). In addition, it was observed 4 cases (21,05%) adverse effects namely dry cough while using Captopril and 1 case (5,26%) of fatigue while using Amlodipine right before night bedtime.