ANALYSIS OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP, PHARMACOPHORE, AND MOLECULAR DOCKING OF TETRACYCLIC INDENOQUINOLINE DERIVATIVES AS ANTICANCER AGENTS
Topoisomerases have been the focus in the treatment of some diseases, such as bacterial gyrase (topoisomerase II) and topoisomerase IV which are the targets of two classes of antibiotic drugs: quinolones and coumarins; as well as, Topoisomerase I and topoisomerase II in cancer treatment. QSAR ana...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/45797 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |