DEVELOPMENT OF FABRIC-BASED NON-ENZIMATIC ELECTROCHEMICAL DEVICE FOR GLUCOSE DETECTION

• Main Author: Jessika
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/46496
• Institution: Institut Teknologi Bandung

Diabetes mellitus is now one of the biggest health problems in the world. Based on WHO data in 2018, around 430 million world populations are diabetics and Indonesia rank sixth in the world with the most diabetic patients (10.3 million population). Quantification methods with laboratory analysis are still widely used in diagnosing types of diseases because of their high efficiency and accuracy. However, these methods require large volumes of test samples and complex sample preparation. The development of point-of-care testing (POCT) device can overcome this problem because test results can be obtained faster, easier, and more affordable. Several studies have developed electrochemical glucose detection methods using glucose oxidase to quantify glucose concentration values with high selectivity and sensitivity, but the stability of this method is susceptible to environmental changes such as pH, humidity, and temperature. Therefore, non-enzymatic glucose sensors are developed to produce better stability and selectivity, as well as lower production costs. In this research, fabric-based electrochemical devices will be fabricated by a stencil method for electrode printing, while batik wax will be used to form the reaction chamber. The electrode material was synthesized with graphite and graphene combined with polyurethane. Some supporting materials that will be used to improve the electrocatalytic performance of the device are rGO-AgNP, CuO, and CNT-AgNP. From the research results, it was found that CNT-AgNP is the best supporting material compared to the other materials in electrochemical measurements for glucose detection, with sensitivity of 0.4629 A/mMcm2, linear coefficient of 0.8543 in the range of 0-10 mM, detection limit of 2.74 mM, and quantification limit of 8.29 mM.