DEVELOPMENT OF PORPHYRIN-ACRIDINE HYBRID COMPOUNDS AS B-DNA BINDERS AND DNA TOPOISOMERASE II ALPHA INHIBITORS: AN IN SILICO STUDY

Porphyrin compounds have been known to accumulate in tumor cells and bind strongly to DNA through several modes of interaction and are thus potential candidates for anticancer agents. Several research have proven that porphyrins are able to trigger cell death through DNA damage and/or changes in...

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Bibliographic Details
Main Author: Nashrullah Muhammad, Hubbi
Format: Dissertations
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/47264
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Institution: Institut Teknologi Bandung
Language: Indonesia