DEVELOPMENT OF PORPHYRIN-ACRIDINE HYBRID COMPOUNDS AS B-DNA BINDERS AND DNA TOPOISOMERASE II ALPHA INHIBITORS: AN IN SILICO STUDY
Porphyrin compounds have been known to accumulate in tumor cells and bind strongly to DNA through several modes of interaction and are thus potential candidates for anticancer agents. Several research have proven that porphyrins are able to trigger cell death through DNA damage and/or changes in...
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Format: | Dissertations |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/47264 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |