ANALYSIS OF METHANOL IN THE HAIR OF MICE INDUCED BY ADULTERATED ALCOHOLIC BEVERAGE
Adulterated alcohol abuse has an impact on catalytic cases among its users. According to this case it is necessary to handle by ensuring the presences of methanol, which is the main ingredients of alduterated alkohol. This study aims to model the detection method for subjects who have metanol exp...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/47274 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Adulterated alcohol abuse has an impact on catalytic cases among its users.
According to this case it is necessary to handle by ensuring the presences of
methanol, which is the main ingredients of alduterated alkohol. This study aims to
model the detection method for subjects who have metanol exposure contained in
adulterated alkohol using mice as experimental animal with qualitative
measurements on their hair. Verification of pharmacological effect is done by
observing analgesic activity using tail flick method. Mice were induced 4 time
every seven days, the treatments consisting of: metanol 73 mg/kgBB and
adulterated alkohol 73 mg/kgBB. The test results showed that all treatment
materials were significantly different pain inhibitory ability (p<0.05) compare to
the control group. These results were followed by a qualitative analysis of metanol
and adulterated alkohol using Fourier Transform Infrared Spectroscopy (FTIR)
which showed no methanol detection in mice hair but detected diethyltoluamide
(DEET) and transflutrin.
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