HYPOFRACTIONATION IN ADVANCED BREAST CANCER

• Main Author: Silvia Putri Raharja Effendi, R
• Format: Final Project
• Language: Indonesia
• Subjects: Fisika
• Online Access: https://digilib.itb.ac.id/gdl/view/47624
• Institution: Institut Teknologi Bandung

In Indonesia, the incidence of cancer ranks 8th in Southeast Asia and ranks 23rd in Asia with the highest incidence of breast cancer. One way to handle cancer cases is radiotherapy. However, the large number of patients is not matched by the number of radiotherapy devices available, causing long queue problems. One of the effort to overcome these problems is by doing hypofractionation. The fraction dose used in this study was 15 x 2.25 Gy and 15 x 3 Gy with a half beam technique. The data reviewed were the dosage constraints on DVH and equivalency of BED value was determined. The application of the first hypofactionation gave the best DVH results among other methods but the BED value did not provide results that were equivalent to standard fractionation. The application of other fractionations gives the opposite result, having a BED value equivalent to standard fractionation but giving bad side effects. Research needs to be done with variations in the dose of other fractions that meet the DVH tolerance dose and is equivalent to the BED of standard fractionation.