STUDY OF ANTIOXIDANT ACTIVITIES OF FICUS LEAVES EXTRACTS AND REVIEW OF CHEMICAL COMPOUNDS AND PHARMACOLOGICAL ACTIVITIES OF FICUS GENUS
Background and purposes: Ficus genus is one of the plants that widely used as a natural source of antioxidant. Diversity of this plant has an attraction to compare antioxidant activities of selected Ficus plants. The puposes of this study were to determine antioxidant activities of leaves extract...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/48621 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Background and purposes: Ficus genus is one of the plants that widely used as a natural
source of antioxidant. Diversity of this plant has an attraction to compare antioxidant
activities of selected Ficus plants. The puposes of this study were to determine
antioxidant activities of leaves extracts from four species of Ficus i.e Ficus
adenosperma, Ficus callosa, Ficus nekbudu and Ficus virens glabella using DPPH
method, determine total phenolic and flavonoid content and analyze the correlation
between total phenolic, flavonoid content with AAI DPPH and also write the review
article about the chemical content and pharmacological activities of Ficus genus.
Methods: Extraction was conducted by reflux using increasing polarity solvents.
Determination of antioxidant activity by DPPH method, total phenolic and total
flavonoid content were carried out by UV-vis spectrophotometry. Correlation of total
phenolic and flavonoid content with AAI DPPH were analyzed using Pearson’s
method. Article review was conducted by collecting and analyzing literatures. Results:
The highest antioxidant activity by DPPH method was shown by ethyl acetate leaves
extract of F. adenosperma with AAI 20,521. The highest total phenolic content was
presented by ethanol leaves extract of F. virens glabella (18.049 g GAE/100 g) and the
highest total flavonoid content was exposed by ethyl acetate leaves extract of F.
nekbudu (26.829 g QE/100 g). Total phenolic content of F. virens glabella leaves
extract had significantly positive correlation with AAI DPPH. In peparing the review
article, 50 literatures were collected and analyzed Conclusions: All leaves extracts of
F. adenosperma had strong to very strong antioxidant activities. Total phenolic content
of F. virens glabella contributed in antioxidant activities by DPPH method. Ficus genus
has many chemical compounds and pharmacological activities.
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