KAJIAN PUSTAKA PENGGUNAAN EKSTRAK SERENOAE REPENDIS FRUCTUS PADA TERAPI PEMBESARAN PROSTAT JINAK (BPH)

Benign Prostatic Hyperlasia (BPH) is a hyperplasia of stroma cell and epitel cell of prostate gland that grew on old male which manifest in the form of lower urinary tract symptoms (LUTS). Choice of drugs therapy which is generally used in Indonesia are ?-blocker and 5?-reductase inhibitor. Phy...

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Bibliographic Details
Main Author: Yunanto, Raynald
Format: Final Project
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/50296
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Institution: Institut Teknologi Bandung
Language: Indonesia
Description
Summary:Benign Prostatic Hyperlasia (BPH) is a hyperplasia of stroma cell and epitel cell of prostate gland that grew on old male which manifest in the form of lower urinary tract symptoms (LUTS). Choice of drugs therapy which is generally used in Indonesia are ?-blocker and 5?-reductase inhibitor. Phytotherapy in the form of Serenoa repens (W. Bartram) small berry (saw palmetto/SR) extract is one of the alternative therapy for BPH. A number of clinical trial study has been performed on SR extract to deterimine it’s efficacy, mechanism and safety. Results showed that the efficacy of SR extract was not consistent enough to be used as alternative therapy. SR extract had an antiandrogenic activity, proliferative proapoptotic activity, antiestrogenic activity and antiinflamatory activity as a main mechanism and good safety record.