STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS

Diabetes Mellitus (DM) is a metabolic disease that affects the regulation of blood sugar, characterized by hyperglycemia. Uncontrolled diabetes leads to serious damage and cause acute or chronic complications. One alternative treatment that can be used for diabetic patients is medicinal herb. Cent...

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Main Author: Faiqoh, Miskiyah
Format: Final Project
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/50304
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Institution: Institut Teknologi Bandung
Language: Indonesia
id id-itb.:50304
spelling id-itb.:503042020-09-23T13:02:19ZSTUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS Faiqoh, Miskiyah Indonesia Final Project Diabetes mellitus, Diabetic, Centella asiatica INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/50304 Diabetes Mellitus (DM) is a metabolic disease that affects the regulation of blood sugar, characterized by hyperglycemia. Uncontrolled diabetes leads to serious damage and cause acute or chronic complications. One alternative treatment that can be used for diabetic patients is medicinal herb. Centella asiatica (CA) is a wild plant that can be found and grown anywhere and has anti-diabetic agent. This literary study aimed to summarize the pharmacological activity of CA on the model of diabetes mellitus. Search data obtained from PubMed with the keyword "Centella asiatica AND (Diabetes mellitus OR Diabetic)" published in 2015-2020. The article search was conducted on 01 June 2020, obtained 8 preclinical articles and 1 clinical article. Based on journals, the main component of CA is asiatic acid and asiaticocide. In preclinical tests, CA can elevate glucose intake through PKB/Akt signaling pathways, reduce oxidative stress and lipid metabolism, play a role in anti-inflammatory, and wound healing process through Wnt/?- catenin signaling pathways. In clinical trials, CA may decrease symptoms of neuropathy. text
institution Institut Teknologi Bandung
building Institut Teknologi Bandung Library
continent Asia
country Indonesia
Indonesia
content_provider Institut Teknologi Bandung
collection Digital ITB
language Indonesia
description Diabetes Mellitus (DM) is a metabolic disease that affects the regulation of blood sugar, characterized by hyperglycemia. Uncontrolled diabetes leads to serious damage and cause acute or chronic complications. One alternative treatment that can be used for diabetic patients is medicinal herb. Centella asiatica (CA) is a wild plant that can be found and grown anywhere and has anti-diabetic agent. This literary study aimed to summarize the pharmacological activity of CA on the model of diabetes mellitus. Search data obtained from PubMed with the keyword "Centella asiatica AND (Diabetes mellitus OR Diabetic)" published in 2015-2020. The article search was conducted on 01 June 2020, obtained 8 preclinical articles and 1 clinical article. Based on journals, the main component of CA is asiatic acid and asiaticocide. In preclinical tests, CA can elevate glucose intake through PKB/Akt signaling pathways, reduce oxidative stress and lipid metabolism, play a role in anti-inflammatory, and wound healing process through Wnt/?- catenin signaling pathways. In clinical trials, CA may decrease symptoms of neuropathy.
format Final Project
author Faiqoh, Miskiyah
spellingShingle Faiqoh, Miskiyah
STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
author_facet Faiqoh, Miskiyah
author_sort Faiqoh, Miskiyah
title STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
title_short STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
title_full STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
title_fullStr STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
title_full_unstemmed STUDI LITERATUR AKTIVITAS FARMAKOLOGI TANAMAN PEGAGAN (CENTELLA ASIATICA (L.) URB.) PADA MODEL DIABETES MELLITUS
title_sort studi literatur aktivitas farmakologi tanaman pegagan (centella asiatica (l.) urb.) pada model diabetes mellitus
url https://digilib.itb.ac.id/gdl/view/50304
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