PENGEMBANGAN FORMULA SISTEM DISPERSI PADAT TABLET IBUPROFEN-PVP K-34
<b>Abstrack</b> <p align=\"justify\"> Solid dispersions of Ibuprofen - PVP K-30 prepared by solvent method, and its characterization by thin layer chromatography , infrared absorption spectroscopy, differential scanning calorimetry, X-ray diffraction analysis and dissolut...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/5343 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | <b>Abstrack</b> <p align=\"justify\"> Solid dispersions of Ibuprofen - PVP K-30 prepared by solvent method, and its characterization by thin layer chromatography , infrared absorption spectroscopy, differential scanning calorimetry, X-ray diffraction analysis and dissolution test had been studied. Result showed that there was no chemical interaction was found beetwen the ingridients. The dissolution rate of system increased by its particle size reduction and transformation of its crystallin forms.The solid dispersion system was formulated into tablet dosage form and compared to that of commercial tablet. Result showed that both tablets fulfilled the dissolution test requirement of the 4th edition Indonesian Pharmacopoeia. |
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