ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)

Citronella (Cymbopogon winterianus Jowitt) is a plant that is known to have antioxidant activity, so this plant has the potential to be used in medicine. However, there has been no research on the activity and active antioxidant isolates of citronella. In this study, citronella was obtained from...

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Main Author: Yulianingtyas
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/54340
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Institution: Institut Teknologi Bandung
Language: Indonesia
id id-itb.:54340
spelling id-itb.:543402021-03-16T07:54:50ZISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT) Yulianingtyas Indonesia Theses antioxidant, isolation, citronella, DPPH INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/54340 Citronella (Cymbopogon winterianus Jowitt) is a plant that is known to have antioxidant activity, so this plant has the potential to be used in medicine. However, there has been no research on the activity and active antioxidant isolates of citronella. In this study, citronella was obtained from Subang Regency (SWA) and West Bandung Regency (SWB). This research was conducted to determine the antioxidant activity of citronella oil, ethanol extract, fractions, and isolates from citronella. Crude drugs and extract were characterized. Extraction was carried out under reflux using ethanol. The extract was monitored and fractionated by liquid-liquid extraction with nhexane and ethyl acetate solvents respectively, then the results were monitored further. The antioxidant activity of oil, ethanol extract, and the three fractions was tested by the method of reducing free radicals 2,2-diphenyl-1-picrylhydrazyl (DPPH). The active fraction was purified by classical column chromatography (CC) and preparative thin layer chromatography (PTLC). The isolates were tested with several spray reagents such as citroborate, AlCl3, FeCl3, and Lieberman-Burchard. The highest antioxidant activity was shown by SWA pulp extract with an IC50 value of 346.096 µg/ml. The isolated Y and K compounds are thought to belong to a group of flavonoid compounds that have a phenol group, with a maximum wavelength of 345 nm and 307 nm. text
institution Institut Teknologi Bandung
building Institut Teknologi Bandung Library
continent Asia
country Indonesia
Indonesia
content_provider Institut Teknologi Bandung
collection Digital ITB
language Indonesia
description Citronella (Cymbopogon winterianus Jowitt) is a plant that is known to have antioxidant activity, so this plant has the potential to be used in medicine. However, there has been no research on the activity and active antioxidant isolates of citronella. In this study, citronella was obtained from Subang Regency (SWA) and West Bandung Regency (SWB). This research was conducted to determine the antioxidant activity of citronella oil, ethanol extract, fractions, and isolates from citronella. Crude drugs and extract were characterized. Extraction was carried out under reflux using ethanol. The extract was monitored and fractionated by liquid-liquid extraction with nhexane and ethyl acetate solvents respectively, then the results were monitored further. The antioxidant activity of oil, ethanol extract, and the three fractions was tested by the method of reducing free radicals 2,2-diphenyl-1-picrylhydrazyl (DPPH). The active fraction was purified by classical column chromatography (CC) and preparative thin layer chromatography (PTLC). The isolates were tested with several spray reagents such as citroborate, AlCl3, FeCl3, and Lieberman-Burchard. The highest antioxidant activity was shown by SWA pulp extract with an IC50 value of 346.096 µg/ml. The isolated Y and K compounds are thought to belong to a group of flavonoid compounds that have a phenol group, with a maximum wavelength of 345 nm and 307 nm.
format Theses
author Yulianingtyas
spellingShingle Yulianingtyas
ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
author_facet Yulianingtyas
author_sort Yulianingtyas
title ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
title_short ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
title_full ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
title_fullStr ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
title_full_unstemmed ISOLATION OF ANTIOXIDANT COMPAUNDS FROM CITRONELLA STALKS (CYMBOPOGON WINTERIANUS JOWITT)
title_sort isolation of antioxidant compaunds from citronella stalks (cymbopogon winterianus jowitt)
url https://digilib.itb.ac.id/gdl/view/54340
_version_ 1822929582383169536