BIOSYNTHESIS OF GOLD NANOPARTICLES (AUNPS) USING CROTON, HANJUANG, CARDAMOM, WALISONGO, KULA LEAF EXTRACT AND FRUIT EXTRACT OF MATOA AS REDUCING AND STABILIZING AGENTS

• Main Author: HAFIDAVI FAHREZY, MUHAMMAD
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/54534
• Institution: Institut Teknologi Bandung

Gold nanoparticles have unique properties and differ from the properties of gold in their bulk size. Thus, gold nanoparticles are widely applied in various fields, especially in the medical field. Recently, research related to gold nanoparticles has been widely conducted. Gold nanoparticles can be synthesized by physical & chemical methods. However, in the process, these methods still use chemical / radiation compounds that are dangerous, toxic and not environmentally benign. Recently, the nanoparticle synthesized by biological method (biosynthesis) has received a lot of attention in the world because there are no/less toxic compounds used or harmful radiation produced by this method. Moreover, the biosynthesis method has several advantages, including simple, economical / inexpensive method, fast process (in minutes), can be scaled-up, can produce large amounts of gold nanoparticles with good size and morphology, free from contamination, and biocompatible. Given that gold nanoparticles are widely applied in the medical field, because of that biocompatible properties are the main requirement. Several studies in the world have shown the success of plant material / plant extracts in synthesizing gold nanoparticles. Therefore, in this research, biosynthesis of gold nanoparticles will be carried out using extracts of tropical plants, such as croton leaves, cardamom, hanjuang, walisongo, kula, and matoa pulp which have never been studied before. A series of experiments began with preparing a solution of gold precursors by dissolving gold in aqua regia solution and preparing an extract solution for each type of plant. The biosynthesis experiment was carried out by adding the plant extract solution into gold precursors solution at a temperature of 80?C. There is a change in the color of the biosynthesis solution (within minutes) which indicates the presence of gold nanoparticles that have formed in the solution. The biosynthesis experiment was optimized by varying the amount of extract solution, synthesis time, and concentration of the precursor solution. The biosynthetic solutions were characterized using UV-Vis and TEM and the gold nanoparticles obtained were characterized using FTIR. In this research, the optimal parameters for the amount of extract solution, synthesis time, and precursor concentration for each plant extract were obtained in synthesizing gold nanoparticles. TEM characterization showed that gold nanoparticles were successfully synthesized for each type of plant extract.