KAJIAN PUSTAKA AKTIVITAS ANTIBAKTERI TUMBUHAN SUKU MYRTACEAE TERHADAP BAKTERI PENYEBAB JERAWAT CUTIBACTERIUM ACNES

• Main Author: Ratnadevati Machdum, Arsanthi
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/56638
• Institution: Institut Teknologi Bandung

Acne is a common but serious skin disease involving the role of the Cutibacterium acnes bacteria. The irrational use of antibiotics has raised concerns about bacterial resistance. In addition, the longterm use of masks during the Covid-19 pandemic increases the risk of acne in face areas covered with masks known as 'maskne'. Natural products derived from plants have been an essential component of skincare since long-ago. One of the natural products that have been widely used and known to be effective in inhibiting the growth of C. acnes is the tea tree oil, which comes from the family of Myrtaceae. This literature review focused on examining the potential of plants in the Myrtaceae family to be developed as candidates for natural anti-acne agents based on analysis of preclinical microbiological data and several clinical studies that had been conducted. Literature data searches were carried out from February to May 2021 through search engines on PubMed Central and ScienceDirect. This literature review has summarized 12 plant species in the Myrtaceae family that show antibacterial activity against C. acnes, including studies related to rhodomyrtone isolates from Rhodomyrtus tomentosa and myrtucommulone from Myrtus communis which have higher antibacterial activity against C. acnes than tea tree oil. Other plants of the Myrtaceae family that have been summarized also show potential as natural anti-acne candidates which can be developed by further testing and designing of anti-acne preparation formulations.