KAJIAN LITERATUR NANO-MOLECULARLY IMPRINTED POLYMER DAN APLIKASINYA DALAM BIDANG FARMASI SEBAGAI DASAR RANCANGAN SINTESIS ADSORBEN SENYAWA DESMOPRESSIN DALAM SAMPEL BIOLOGIS
Molecularly Imprinted Polymer (MIP) is a polymeric matrix with specific recognition cavities of template/analyte molecule, which is formed by polymerization reaction of functional monomer, as a product obtained from Molecularly Imprinted Technology (MIT). Nano-MIP is a nano-scale MIP, a produc...
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Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/56640 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |
Summary: | Molecularly Imprinted Polymer (MIP) is a polymeric matrix with specific recognition cavities of
template/analyte molecule, which is formed by polymerization reaction of functional monomer, as
a product obtained from Molecularly Imprinted Technology (MIT). Nano-MIP is a nano-scale MIP, a
product produced by combination of nanotechnology and MIT. The utilization of nano-MIP has a
great potency in pharmaceutical field, especially with the continuation of nano-MIP development
in the future. Desmopressin is a synthetic analogue of arginine vasopressin. Desmopressin has antidiuretic activity and blood coagulating effect. Since 2011, World Anti-Doping Agency (WADA) has
been including desmopressin in List of Prohibited Substances and Methods within the category of
diuretics and masking agents doping. Study with literature review method was held to obtain deep
understanding about nano-MIP and it’s characteristics, nano-MIP synthesis techniques, and
application of nano-MIP in pharmaceutical field. From the literature review, a systematic plan to
produce nano-MIP as adsorbent for desmopressin from biological sample, was designed.
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