KAJIAN PUSTAKA: FITOKIMIA DAN AKTIVITAS FARMAKOLOGI TUMBUHAN MARGA ALLIUM

• Main Author: Aulia, Rizka
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/56657
• Institution: Institut Teknologi Bandung

The approximately 850 species of the genus Allium are distributed worldwide. Some species have been traditionally used as food and their medicinal properties. This review focusing on traditional uses, phytochemical aspects and pharmacological activities. This review aims to provide an overview of the current state of knowledge chemical constituents, pharmacological activities, clinical studies and safety of Allium species, to identify the therapeutic potential of Allium species and further directions of research. The selection of relevant data was made through a search using Google Scholar dan PubMed website. Plant taxonomy was validated by Worldfloraonline website. Twenty-five Allium species were collected in this study. Allium genus contained allicin. Consumption of a high dose of allicin could cause discomfort in some individuals. This review confirmed that some Allium species were good sources of traditional medicine for treatment, particularly as antibacterial, antifungal, antiviral, antioxidant, antihyperlipidemic, antihypertensive, antidiabetic, anti-inflammatory, anticancer and neuroprotective effects. It needs further promising investigations on Allium compounds, especially allicin, quercetin and steroidal saponin to aid drug development and drug discovery. In addition, anticancer and antibacterial for antibiotics-resistant bacterial strains, should have priority in future pharmacological studies.