STUDY ON ADSORPTION OPTIMIZATION OF PHARMACEUTICAL CONTAMINANT CARBAMAZEPINE IN WATER WITH SEPIOLITE NATURAL CLAY USING RESPONSE SURFACE METHODOLOGY

• Main Author: Nabilla, Itsna
• Format: Final Project
• Language: Indonesia
• Subjects: Teknik saniter dan perkotaan; teknik perlindungan lingkungan
• Online Access: https://digilib.itb.ac.id/gdl/view/57938
• Institution: Institut Teknologi Bandung

Currently, pharmaceutical contaminants are a recent issue related to environmental pollution. Pharmaceutical contaminants are found in Wastewater Treatment Plants, Water Treatment Plants, rivers, lakes and even groundwater. Carbamazepine is one of the toxic pharmaceutical contaminants found in almost all places. Carbamazepine is a very persistent compound in nature. Carbamazepine has been studied to accumulated in flora and fauna. In addition, it also causes damage to chicken embryos and zebrafish embryos. Therefore, it is necessary to remove pharmaceutical contaminants from environmental components. One of the significant methods for removing these pharmaceutical compounds is adsorption. Among various types of adsorbents, clay is a promising adsorbent because it is environmentally friendly and available in large quantities. This study aims to determine the optimum conditions of adsorption of Carbamazepine compounds using Sepiolite clay. Adsorption is modelled on 3 main factors, namely the concentration of the solution (1-10 mg/L), the pH of the solution (3-11) and the dose of the clay adsorbent to the solution (4-20 g/L). The adsorption experiment and analysis were compiled from the model generated using the Response Surface Methodology Box Behnken Design. The optimum conditions for adsorption of carbamazepine pharmaceutical contaminants using sepiolite clay occurred at a concentration of 9,8 mg/L; pH value 5,9; and the adsorbent dose was 18,2 g/L with an allowance of 51,9%. In effect of operating parameters, large solution concentration, acid pH tends to be neutral and a large adsorbent dose gives a higher removal value.