SINTESIS NANOPARTIKEL PERAK MENGGUNAKAN BIOREDUKTOR EKSTRAK KULIT KACANG (ARACHIS HYPOGEA L.) SERTA KAJIAN PUSTAKA KARAKTERISASI DAN AKTIVITAS ANTIMIKROBANYA

• Main Author: Nurafifah, Hilma
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/61883
• Institution: Institut Teknologi Bandung

The silver nanoparticle is one of the nanotechnology discoveries with good chemical stability and conductivity, antifungal, and antibacterial activity. The application of the eco-friendly biological synthesis method in the formation of silver nanoparticles has been widely done, as in this study with utilizing peanut (Arachis hypogea L.) skin extract as the natural reducing agent. This study is divided into the experimental study of silver nanoparticle synthesis and literature study to examine the characteristic of silver nanoparticles and their antimicrobial activity toward the E. coli and S. aureus bacteria, and the C. albicans and A. niger fungi. The silver nanoparticle was obtained with microwave synthesis method with the characteristic of maximum wavelength 440 nm with the concentration of optimum silver nitrate (AgNO3) 1.5 mM. According to the literature study, the silver nanoparticle is spherical, 2-100 nm in size with even distribution, good stability, and cubic crystal structure. The silver nanoparticle has the potency of antimicrobial activity with the mechanism of silver nanoparticle interaction with lipopolysaccharide and protein-membrane which causes cellular membrane damage, disturbing membrane permeability, and triggering an intracellular leak. Silver nanoparticle also induces the formation of reactive oxygen species which interfere with the microbe cell and causes cellular death.