RENCANA PENGEMBANGAN METODE ANALISIS PENETAPAN KADAR ?-MANGOSTIN DALAM SUPLEMEN MAKANAN DENGAN METODE KROMATOGRAFI CAIR KINERJA TINGGI

• Main Author: Atikah, Rona
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/61921
• Institution: Institut Teknologi Bandung

?-Mangostin (AMG) is a secondary metabolite of xanthone derivative which was discovered in Garcinia mangostana rind. AMG contributes to the maintenance of normal cognitive functions and LDL particles from oxidative damage. Pure AMG product demand has been increasing in the last few decades. Currently, AMG isolate is available in capsule dietary supplements. It is necessary to establish a standardisation of AMG preparations to ensure the product quality, efficacy, and safety for its users. Therefore, an analytical method is needed to measure the AMG content in dietary supplements, but none of validated high performance liquid chromatography (HPLC) method has been found to analyse AMG isolates in a capsule specifically. Through literature review, various AMG quantification methods references have been collected, reviewed, compared, so that a new assay of AMG in capsule dietary supplements using HPLC can be proposed. This research is proposed to be a simple, effective, and efficient AMG analysis method as an inventory that can be validated through experiments in the future.