EVALUASI PENGGUNAAN OBAT PASIEN ANAK RAWAT INAP DENGAN DIAGNOSIS DEMAM TIFOID DAN PARATIFOID DI RUMAH SAKIT MUHAMMADIYAH BANDUNG

• Main Author: Faizah, Shaffiati
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/62172
• Institution: Institut Teknologi Bandung

Typhoid fever is bacterial infection disease with high mortality in Indonesia. The problems including clinical symptoms are varied from mild to severe with dangerous complication and increased in resistance to the medicine that is given to the sick person. Based on the data of healthcare in West Java in the year 2007, typhoid fever rank second as the cause of death in children between the age of 5 to 14 years old. The percentage reaches 13% in urban area and 3,8% in rural area. The objectives of this research are to determine a treatment pattern and to make an assessment of the accuracy of the treatment to the disease. The research was done by doing a descriptive study based on evaluative. It was done retrospectively by analysis of the patient’s medical record. The patients are children who was stayed at the hospital and was diagnosed by typhoid fever by July 1 to December 31 2012. The treatment pattern of patient with typhoid fever were antibacterial, analgesic and antipyretic, and treatment nutritions. Ceftriaxone was an antibacterial that was most commonly used as single medication for 50,49% and the use of combination of ceftriaxone and amikacin was 13,59% with additional diagnosis. Paracetamol was an analgesic and antipyretic that was most commonly used (56,45%). 99,03% parenteral nutritions and oral nutritions were accordant to guideline. Drugs administered via the oral route was 66,75% and parenteral route was 31,96%. Compatibility between indication and the doses given was 96,05% and 98,83% respectively. Duplication was found in the use of combination of ceftriaxone and cefixime. The treatment duration for patient who was given antibiotic were varied between 4 days (25,46%), 6 days (23,30%), 5 days (15,54%), and 3 days (12,62%). Potential drug interaction incidence was 5,76% with each type of drug interaction are major (0,08%). Adverse drug reactions (ADR) incidence was not found.