UJI DAYA REPELENSI DAN WAKTU PROTEKSI TOTAL EKSTRAK DAUN TEMBELEKAN (LANTANA CAMARA L) TERHADAP NYAMUK AEDES AEGYPTI L

• Main Author: William Hendri, Mark
• Format: Final Project
• Language: Indonesia
• Subjects: Ilmu hayati ; Biologi
• Online Access: https://digilib.itb.ac.id/gdl/view/63133
• Institution: Institut Teknologi Bandung

Dengue fever is a viral infection caused by Dengue virus. One of the biggest factors why dengue fever infection rate in Indonesia is high, is the compatibility between climate and dengue virus’ vector, Aedes aegypti. Vector control and infection prevention by vector is needed such as repellent. Based on research that has been done before, Lantana camara has reducing effect on landing frequency on human skin. The goal of this research is to determine Effective Dose (ED99) of Lantana camara crude extract, mean Complete Protection Time (CPT), and indentify content of secondary metabolites of crude Lantana camara extract by GC-MS. Lantana camara leaves are extracted with maceration method by methanol 80% for 3 days. The crude extract is divided into 5 different concentrations, 0.06mg/cm2, 0.18mg/cm2, 0.3mg/cm2, 0.42mg/cm2, and 0.54mg/cm2. All statistic calculations are calculated using IBM SPSS 25 with 95% confidence. The results showed that crude Lantana camara extract has a percentage of protection from the maximum to the largest sequential dose is 74.2 ± 0.04%, 88.8 ± 0.02%, 90.5 ± 0.05%, and 100% for the rest two concentrations. Lantana camara extract has ED99 of 0.3mg/cm2 as repellent againts Aedes aegypti. The mean Complete Protection Time of Lantana camara extract is 2.5 hours (150 minutes) on ED99. GC-MS analysis results shows alkaloid, terpen, phenol, and indole. Lantana camara has the potential as repellent againts Aedes aegypti