FABRICATION OF CARBON-GOLD NANODENDRITES COMPOSITE USING ELECTRODEPOSITION TECHNIQUE FOR SCREEN-PRINTED CARBON ELECTRODE-BASED ASCORBIC ACID BIOSENSOR APPLICATION

• Main Author: Ariasena, Eduardus
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/65812
• Institution: Institut Teknologi Bandung

Gold nanodendrites or AuND are one type of gold nanoparticles that are widely used to improve the electrocatalytic performance of electrochemical sensors for their large active surface area. One way to synthesize gold nanodendrites is to use electrodeposition method. This method is easy to conduct and very efficient because it can simultaneously integrate gold nanodendrites on the electrode surface while synthesizing them. One type of electrochemical sensor electrode that has been widely studied is the screen-printed carbon electrode or SPCE. This type of electrode combines the conventional three-electrode system commonly used in laboratories, into a small, portable substrate that can be utilized for a cheaper and more practical point-of-care detection. SPCE surface can be modified using nanomaterials such as gold nanodendrites to fabricate a nonenzymatic electrochemical biosensors that can be used to detect important substances in the body. In this final project, an electrodeposition synthesis of gold nanodendrites was conducted on the surface of the SPCE. In the synthesis process, optimization was carried out to produce electrodes with the best electrochemical performance. The AuND structure formed on the SPCE surface was then analyzed using the FESEM, EDS, and XRD characterization methods to ensure the formation of AuND with optimal characteristics. The optimized SPCE-AuND was then applied as a nonenzymatic electrochemical biosensor used to selectively detect ascorbic acid. Based on some examinations using differential pulse voltammetry (DPV) technique, the detection performance of the biosensors was obtained as detection limit (LOD), quantification limit (LOQ), and linear range with a value of 10,56 ?M; 31,99 ?M; dan 100–2000 ?M respectively. This performance value is still within the normal range of ascorbic acid concentration in human tears, so there is a potential application of the SPCE-AuND as a tear-based non-invasive ascorbic acid biosensor.