KAJIAN PUSTAKA PEMANFAATAN PEGAGAN SEBAGAI TERAPI PENUNJANG PENYAKIT ALZHEIMER DAN PENGGUNAANNYA SEBAGAI SARANA EDUKASI DALAM BENTUK BUKU DIGITAL

• Main Author: Lin Richel A, Michelle
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/66287
• Institution: Institut Teknologi Bandung

Alzheimer's is a disorder in the body associated with a decline in cognitive abilities that can affect the sufferer's daily habits, can cause dependence on others, disability, and even lead to death for the sufferer. Alzheimer's has physical, psychological, social, and economic impacts. These impacts affect not only people living with the disease, but also for caregivers, families, and the surrounding community. To improve the quality of life of the sufferer, it is necessary to have a therapy that can improve the cognitive ability of the patient. Gotu kola or Centella asiatica is a plant that has been used by the people of China and India to treat various diseases since ancient times which is believed to have a neuroprotectant and neurogenerative effect. With these claims, various studies were carried out to prove the truth of the claims recognized by the community. Based on the literature found on search engines from 2010 to the present, it was found that gotu kola is widely used empirically to treat various diseases ranging from skin diseases to psychiatric in India, China, and countries in Southeast Asia. Based on research, the dose of Centella asiatica which is considered effective for improving cognitive is 500mg/kg body weight per day. In addition, based on the mechanism of testing in animals and humans, gotu kola is proven to be able to improve cognitive in experimental animals and research subjects through various mechanisms of action, the end result is that it improves cognitive and improves behavior.