MODIFIED SCREEN-PRINTED CARBON ELECTRODE AS AN ELECTROCHEMICAL BIOSENSOR FOR GLUCOSE DETECTION

• Main Author: Nur'aviana Rizalputri, Lavita
• Format: Final Project
• Language: Indonesia
• Subjects: Teknik (Rekayasa, enjinering dan kegiatan berkaitan)
• Online Access: https://digilib.itb.ac.id/gdl/view/69656
• Institution: Institut Teknologi Bandung

Glucose is one of the most important substances for medical check-up. Therefore, many studies are being done to find technology that can carry out research-level analysis in a non-invasive and fast way to detect glucose. Making a portable sensor that can properly support the results of sample testing is a solution to this problem. Screen-printed carbon electrode (SPCE) is one of the electrodes that can be used as a portable sensor because of its small size. However, the working electrodes from SPCE must be modified with additional material to improve the performance. Many factors determine the modification such as the deposition method and the material itself. In this study, the SPCE modification was carried out by drop-casting method and using enzymatic and non-enzymatic materials. The enzymatic material consists of glucose oxidase (GOx) while the non-enzymatic material is Graphene-Fe3O4, CNT-Fe3O4 and Co-MOF. From these materials, SPCE only can detect glucose when modified by Co-MOF. SPCE performance as a detection sensor has a characteristic measurement error of 1.7% and selective to glucose when compared with urea and NaCl, but doesn’t have good sensitivity and stability for variations in glucose concentration.