QUALITATIVE STUDY OF LEVEL KNOWLEDGE AND APPROPRIATE USE OF CHOLCHICINE IN ATTACT AND PREVENTIVE GOUT ARTHRITIS THERAPY AT SEVERAL KIMIA FARMA PHARMACY IN BANDUNG

• Main Author: Nisa, Khairun
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/70812
• Institution: Institut Teknologi Bandung

Gout arthritis (GA) is one of health problems in Indonesia which has increase since last 5 years. GA attacks occured due to increase the level of uric acid serum (hyperuricemia) > 6,8 mg/dL which caused inflammation and joints pain. Untreated GA risks to permanent damage of joint tissue including chronic kidney disease. Cholchicine were common chosen for attacked or preventive GA therapy. Better knowledge about GA and cholchicine very important to achieved goal therapy and prevented adverse effect as program of WHO “patient for patient safety” which involved patient in their treatment safety. This study aimed to describe the level of patient knowledge and appropriate used of cholchicine in attacked and prevention GA at several Kimia Farma Bandung Pharmacy. This study used a descriptive-observational design with a cross-sectional design. Determination of sample used purposive sampling method. The instrument of this study were questionnaires for interview that has passed the validity and reliability test. Analysis conducted by thematic approach method to find pattern of patient about their knowledge and appropiate used of cholchicine. The result showed that the level of patient knowledge about cholchicine was poor (20.49%) with the lowest aspect was risk and dose of chochicine (10.31%; 11.34%). Patient knowledge about GA also poor (24.97%). The level of appropriate used of cholchicine very low (3.9%) and most patient unsure about the right way to take cholchicine for therapy (90.04%). Side effect of cholchicine occured was 24% with the major case affect the gastrointestinal such as diare, nausea and vomit. Based on the result of this study found that the urgency in increase patient knowledge of GA and appropriate used of cholchicine. This study provided an overview about the aspect that need to improve by pharmacy service particularly in gout patient.