DISSOLUTION ENHANCEMENT OF ENTACAPONE FROM FIXED DOSE COMBINATION TABLETS LEVODOPA/CARBIDOPA/ENTACAPONE WITH MICROENVIRONMENTAL PH MODIFICATION TECHNIQUES
Entacapone is a catechol nitro compound used in the treatment of Parkinson's disease in combination with carbidopa and levodopa. Entacapone is classified in Biopharmaceutical Classification System (BCS) 4, with low solubility and membrane permeability. Based on this, entacapone needs to b...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/73968 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |