EFFECTS OF SPINY AMARANTH LEAF (AMARANTHUS SPINOSUS L.) EXTRACT AND KATUK LEAF (SAUROPUS ANDROGYNUS (L.) MERR.) EXTRACT COMBINATION AS BREAST MILK PRODUCTION ENHANCER IN FEMALE WISTAR RATS

• Main Author: Inez Wibowo, Maria
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/73979
• Institution: Institut Teknologi Bandung

Breast milk is an exclusive food that must be given to infants aged 0-6 months. However, in the process of breastfeeding, there are often some problems such as low milk supply. Some solution to increase breast milk production is to consume foods that are lactagogues, such as katuk leaves (Sauropus androgynus (L.) Merr.) and spiny amaranth leaves (Amaranthus spinosus L.). This study aimed to determine which dose of extract combination that was more effective to increase milk production in rats. This study also wanted to determine the effectiveness of the dose of a combination of spiny amaranth leaves and katuk leaves to increase breast milk production compared to each single extract dose. Spiny amaranth leaves and katuk leaves were extracted by maceration method with 70% ethanol solvent. The increase of milk production was tested by administering the extract orally with dose A and dose B in female Wistar rats who were lactating for 14 days. The parameters assessed in this study was the weight of the pups at 4 endpoints, namely on the 2nd, 4th, 8th and 15th days of lactation. In this study, the average acquisition of breast milk from combination extract with dose A (average 6.45±1.82 g) was higher than the combination extract dose B (average 5.11±1.10 g). In this study, it was also found that the combination extract group dose A (average 6.45±1.82 g) produced milk gains that were not significantly different from a single extract of spiny amaranth leaves dose 100 mg / kg BW (average 5.04±2.62 g) or single extract of katuk leaves dose 100 mg / kg BW (average 6.14±2.84 g). The acquisition of milk in combination extract dose A is higher but does not differ significantly when compared to combination extract dose B, single extract of spiny amaranth leaves 100 mg / kg BW, and single extract of katuk leaves 100 mg / kg BW.